{"id":22138,"date":"2023-12-16T21:12:50","date_gmt":"2023-12-16T21:12:50","guid":{"rendered":"https:\/\/dupmecp2.eu\/?p=22138"},"modified":"2023-12-20T18:44:05","modified_gmt":"2023-12-20T18:44:05","slug":"hg204-huidagene","status":"publish","type":"post","link":"https:\/\/dupmecp2.eu\/el\/hg204-huidagene\/","title":{"rendered":"Huidagene: \u039c\u03b9\u03b1 \u03c0\u03bf\u03bb\u03bb\u03ac \u03c5\u03c0\u03bf\u03c3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 CRISPR-CAS13 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03a3\u03b1\u03b3\u03ba\u03ac\u03b7 (\u039a\u03af\u03bd\u03b1)"},"content":{"rendered":"<p>\u0397 Huidagene Therapeutics \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03b5\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1 \u03b2\u03b9\u03bf\u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u03bc\u03b5 \u03ad\u03b4\u03c1\u03b1 \u03c4\u03b7 \u03a3\u03b1\u03b3\u03ba\u03ac\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf \u039d\u03b9\u03bf\u03c5 \u03a4\u03b6\u03ad\u03c1\u03c3\u03b5\u03ca, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b5\u03c0\u03b9\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03ba\u03ac\u03bb\u03c5\u03c8\u03b7, \u03c4\u03b7 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03bd\u03ad\u03c9\u03bd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf CRISPR. \u0397 \u03b5\u03c4\u03b1\u03b9\u03c1\u03b5\u03af\u03b1 \u03b5\u03c0\u03b9\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03bc\u03c5\u03ca\u03ba\u03ad\u03c2, \u03bf\u03c6\u03b8\u03b1\u03bb\u03bc\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ad\u03c2.<\/p>\n\n\n\n<p>\u0397 Huidagene \u03b1\u03bd\u03ad\u03c0\u03c4\u03c5\u03be\u03b5 \u03c4\u03bf HG204, \u03ad\u03bd\u03b1\u03bd \u03b1\u03b4\u03b5\u03bd\u03bf-\u03c3\u03c5\u03bd\u03b4\u03b5\u03b4\u03b5\u03bc\u03ad\u03bd\u03bf \u03b9\u03b9\u03ba\u03cc \u03c6\u03bf\u03c1\u03ad\u03b1 (AAV) \u03c0\u03bf\u03c5 \u03bc\u03b5\u03c4\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03ad\u03bd\u03b1 \u03bd\u03ad\u03bf \u03c3\u03cd\u03bc\u03c0\u03bb\u03bf\u03ba\u03bf CRISPR-Cas13 \u03c3\u03b5 \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1. \u03a3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03c3\u03cd\u03bd\u03b4\u03c1\u03bf\u03bc\u03bf \u03b4\u03b9\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd \u03c4\u03bf\u03c5 MECP2, <strong>\u03a4\u03bf HG204 \u03b1\u03c0\u03bf\u03c3\u03ba\u03bf\u03c0\u03b5\u03af \u03c3\u03c4\u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c5\u03c0\u03b5\u03c1\u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 MeCP2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03c0\u03b1\u03b3\u03c9\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03b9\u03ba\u03bf\u03b4\u03cc\u03bc\u03b7\u03c3\u03b7\u03c2 \u03c4\u03bf\u03c5 \u03c5\u03c0\u03b5\u03c1\u03b5\u03ba\u03c6\u03c1\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 RNA MECP2.<\/strong> \u0391\u03c5\u03c4\u03cc \u03c4\u03bf \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03bf \u03c5\u03c0\u03bf\u03c8\u03ae\u03c6\u03b9\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03ad\u03c7\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03bd\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03cd\u03c3\u03b5\u03b9 \u03c4\u03bf MDS \u03bc\u03b5 \u03bc\u03af\u03b1 \u03bc\u03cc\u03bd\u03bf \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7.<\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>\u039f \u03bf\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03bc\u03b1\u03c2 \u03b5\u03af\u03c7\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c5\u03b6\u03b7\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5 \u03c4\u03bf\u03c5\u03c2 \u03b7\u03b3\u03ad\u03c4\u03b5\u03c2 \u03c4\u03b7\u03c2 Huidagene \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03bc\u03ac\u03b8\u03b5\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03ba\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03bf \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b9 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd. <strong>\u03a0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03bf\u03c5 HG204 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03b5\u03be\u03b1\u03bd\u03b8\u03c1\u03c9\u03c0\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03bf \u03c0\u03bf\u03bd\u03c4\u03b9\u03ba\u03bf\u03cd MDS \u03ad\u03b4\u03b5\u03b9\u03be\u03b1\u03bd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 MeCP2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.<\/strong> \u0395\u03bd\u03ce \u03c0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b5\u03bd\u03b8\u03b1\u03c1\u03c1\u03c5\u03bd\u03c4\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1, \u03b1\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b7 \u03b4\u03b5\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03c0\u03cc\u03b4\u03b5\u03b9\u03be\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03b1\u03c3\u03c4\u03c1\u03b5\u03c8\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \u03c4\u03bf\u03c5 MDS \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 MECP2 (\u03cc\u03c0\u03c9\u03c2 \u03b5\u03af\u03c7\u03b5 \u03ae\u03b4\u03b7 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03bc\u03b5 \u03c4\u03b7 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 ASO \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03ba\u03b1\u03b8\u03b7\u03b3\u03b7\u03c4\u03ae H. Zoghbi \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03bf\u03c5).<\/p>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>\u0397 Huidagene \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03b4\u03b9\u03ba\u03b1\u03c3\u03af\u03b1 \u03bf\u03bb\u03bf\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7\u03c2 \u03c4\u03c9\u03bd \u03c0\u03c1\u03bf\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5\u03bb\u03b5\u03c4\u03ce\u03bd \u03bc\u03b5 \u03c4\u03bf HG204 \u03ba\u03b1\u03b9 \u03b5\u03c4\u03bf\u03b9\u03bc\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bc\u03b9\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c3\u03c4\u03b7\u03bd \u039a\u03af\u03bd\u03b1, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03b9\u03c3\u03c4\u03b5\u03af \u03bd\u03b1 \u03be\u03b5\u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b1 \u03bc\u03ad\u03c3\u03b1 \u03c4\u03bf\u03c5 2024. <\/strong>\u0395\u03ac\u03bd \u03b7 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03b1\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03c0\u03b9\u03c4\u03c5\u03c7\u03ae\u03c2, \u03b7 Huidagene \u03b8\u03b1 \u03c0\u03c1\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1\u03c4\u03af\u03c3\u03b5\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03c3\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c7\u03ce\u03c1\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03bf\u03b9 \u0397\u03a0\u0391 \u03ba\u03b1\u03b9 \u03b7 \u0395\u03c5\u03c1\u03ce\u03c0\u03b7 \u03c4\u03bf 2025-2026.<\/p>\n\n\n\n<p><br>\u03a3\u03c4\u03b9\u03c2 31 \u039f\u03ba\u03c4\u03c9\u03b2\u03c1\u03af\u03bf\u03c5, \u03bf FDA (\u039f\u03c1\u03b3\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03a4\u03c1\u03bf\u03c6\u03af\u03bc\u03c9\u03bd \u03ba\u03b1\u03b9 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd, \u03b7 \u03c5\u03b3\u03b5\u03b9\u03bf\u03bd\u03bf\u03bc\u03b9\u03ba\u03ae \u03b1\u03c1\u03c7\u03ae \u03c4\u03c9\u03bd \u0397\u03a0\u0391) \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b5 \u03c3\u03c4\u03bf HG204 \u03c4\u03cc\u03c3\u03bf \u03c4\u03bf\u03bd \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03cc \u03c3\u03c0\u03ac\u03bd\u03b9\u03b1\u03c2 \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5 \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03c4\u03bf\u03bd \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03cc \u03bf\u03c1\u03c6\u03b1\u03bd\u03bf\u03cd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5. \u0391\u03c5\u03c4\u03cc\u03c2 \u03bf \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03ad\u03bd\u03b1 \u03c0\u03c1\u03ce\u03c4\u03bf \u03b2\u03ae\u03bc\u03b1 \u03c0\u03c1\u03bf\u03c2 \u03bc\u03b9\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae \u03b5\u03ba\u03c4\u03cc\u03c2 \u039a\u03af\u03bd\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03b5\u03c0\u03b9\u03c4\u03c1\u03ad\u03c8\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c4\u03b1\u03c7\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b5\u03be\u03ad\u03c4\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03ba\u03ad\u03bb\u03bf\u03c5 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03c7\u03ce\u03c1\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5. \u0391\u03bd \u03ba\u03b1\u03b9 \u03b7 \u03b5\u03af\u03b4\u03b7\u03c3\u03b7 \u03ae\u03c4\u03b1\u03bd \u03b5\u03bd\u03c4\u03b5\u03bb\u03ce\u03c2 \u03b1\u03c0\u03c1\u03bf\u03c3\u03b4\u03cc\u03ba\u03b7\u03c4\u03b7, \u03c6\u03ad\u03c1\u03bd\u03b5\u03b9 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b7 \u03b5\u03bb\u03c0\u03af\u03b4\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1.<\/p>\n\n\n\n<p>\u0397 \u03bf\u03bc\u03ac\u03b4\u03b1 \u03bc\u03b1\u03c2 \u03b8\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03b5\u03af\u03bd\u03b5\u03b9 \u03c3\u03b5 \u03b5\u03c0\u03b1\u03c6\u03ae \u03bc\u03b5 \u03c4\u03b7\u03bd Huidagene \u03ba\u03b1\u03b9 \u03b8\u03b1 \u03b5\u03bd\u03b7\u03bc\u03b5\u03c1\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ba\u03bf\u03b9\u03bd\u03cc\u03c4\u03b7\u03c4\u03ac \u03bc\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03c5\u03c7\u03cc\u03bd \u03bd\u03ad\u03b5\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large is-resized\"><img decoding=\"async\" data-src=\"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene_Pipeline_2023_white-edited.png\" alt=\"\" class=\"wp-image-22144 lazyload\" style=\"--smush-placeholder-width: 1920px; --smush-placeholder-aspect-ratio: 1920\/1080;width:840px;height:auto\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" \/><\/figure>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-background wp-element-button\" href=\"https:\/\/www.huidagene.com\/new\/news\/48\" style=\"border-radius:16px;background-color:#f7a13c\" target=\"_blank\" rel=\"noreferrer noopener\">\u03a3\u03c4\u03bf \u03b4\u03b5\u03bb\u03c4\u03af\u03bf \u03c4\u03cd\u03c0\u03bf\u03c5<\/a><\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Huidagene Therapeutics is a biotechnology company based in Shanghai and New Jersey, focusing on discovering, engineering, and developing novel CRISPR-based medicines. The company focuses on muscular, ophthalmic and neurological disorders. [&hellip;]<\/p>","protected":false},"author":1,"featured_media":22150,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[87],"tags":[],"class_list":["post-22138","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China) - DupMECP2<\/title>\n<meta name=\"description\" content=\"A potential new perspective for the treatment of MECP2 duplication syndrome with Huidagene&#039;s CRIPSR-Cas13. The drug candidate HG204 demonstrated a significant reduction of MeCP2 protein and reversal of the symptoms.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dupmecp2.eu\/el\/hg204-huidagene\/?lang=en\" \/>\n<meta property=\"og:locale\" content=\"el_GR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China) - DupMECP2\" \/>\n<meta property=\"og:description\" content=\"A potential new perspective for the treatment of MECP2 duplication syndrome with Huidagene&#039;s CRIPSR-Cas13. The drug candidate HG204 demonstrated a significant reduction of MeCP2 protein and reversal of the symptoms.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/dupmecp2.eu\/el\/hg204-huidagene\/?lang=en\" \/>\n<meta property=\"og:site_name\" content=\"DupMECP2\" \/>\n<meta property=\"article:published_time\" content=\"2023-12-16T21:12:50+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2023-12-20T18:44:05+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png\" \/>\n\t<meta property=\"og:image:width\" content=\"318\" \/>\n\t<meta property=\"og:image:height\" content=\"112\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Caroline\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u03a3\u03c5\u03bd\u03c4\u03ac\u03c7\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc\" \/>\n\t<meta name=\"twitter:data1\" content=\"Caroline\" \/>\n\t<meta name=\"twitter:label2\" content=\"\u0395\u03ba\u03c4\u03b9\u03bc\u03ce\u03bc\u03b5\u03bd\u03bf\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c2 \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 \u03bb\u03b5\u03c0\u03c4\u03ac\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#article\",\"isPartOf\":{\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en\"},\"author\":{\"name\":\"Caroline\",\"@id\":\"https:\/\/dupmecp2.eu\/#\/schema\/person\/b41e8cbba153cd974ee340386af279ee\"},\"headline\":\"Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China)\",\"datePublished\":\"2023-12-16T21:12:50+00:00\",\"dateModified\":\"2023-12-20T18:44:05+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en\"},\"wordCount\":313,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/dupmecp2.eu\/#organization\"},\"image\":{\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage\"},\"thumbnailUrl\":\"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png\",\"articleSection\":[\"News\"],\"inLanguage\":\"el\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en\",\"url\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en\",\"name\":\"Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China) - DupMECP2\",\"isPartOf\":{\"@id\":\"https:\/\/dupmecp2.eu\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage\"},\"image\":{\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage\"},\"thumbnailUrl\":\"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png\",\"datePublished\":\"2023-12-16T21:12:50+00:00\",\"dateModified\":\"2023-12-20T18:44:05+00:00\",\"description\":\"A potential new perspective for the treatment of MECP2 duplication syndrome with Huidagene's CRIPSR-Cas13. The drug candidate HG204 demonstrated a significant reduction of MeCP2 protein and reversal of the symptoms.\",\"breadcrumb\":{\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#breadcrumb\"},\"inLanguage\":\"el\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"el\",\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage\",\"url\":\"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png\",\"contentUrl\":\"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png\",\"width\":318,\"height\":112},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/dupmecp2.eu\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"News\",\"item\":\"https:\/\/dupmecp2.eu\/category\/news\/?lang=en\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/dupmecp2.eu\/#website\",\"url\":\"https:\/\/dupmecp2.eu\/\",\"name\":\"DupMECP2\",\"description\":\"EU\",\"publisher\":{\"@id\":\"https:\/\/dupmecp2.eu\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/dupmecp2.eu\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"el\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/dupmecp2.eu\/#organization\",\"name\":\"DupMECP2\",\"url\":\"https:\/\/dupmecp2.eu\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"el\",\"@id\":\"https:\/\/dupmecp2.eu\/#\/schema\/logo\/image\/\",\"url\":\"\",\"contentUrl\":\"\",\"caption\":\"DupMECP2\"},\"image\":{\"@id\":\"https:\/\/dupmecp2.eu\/#\/schema\/logo\/image\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\/\/dupmecp2.eu\/#\/schema\/person\/b41e8cbba153cd974ee340386af279ee\",\"name\":\"Caroline\",\"sameAs\":[\"https:\/\/dupmecp2.eu\"],\"url\":\"https:\/\/dupmecp2.eu\/el\/author\/417a2385dc37aa45\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Huidagene: \u039c\u03b9\u03b1 \u03c0\u03bf\u03bb\u03bb\u03ac \u03c5\u03c0\u03bf\u03c3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 CRISPR-CAS13 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03a3\u03b1\u03b3\u03ba\u03ac\u03b7 (\u039a\u03af\u03bd\u03b1) - DupMECP2","description":"\u039c\u03b9\u03b1 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03bd\u03ad\u03b1 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 \u03b4\u03b9\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd \u03c4\u03bf\u03c5 MECP2 \u03bc\u03b5 \u03c4\u03bf CRIPSR-Cas13 \u03c4\u03b7\u03c2 Huidagene. \u03a4\u03bf \u03c5\u03c0\u03bf\u03c8\u03ae\u03c6\u03b9\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf HG204 \u03ba\u03b1\u03c4\u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 MeCP2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/dupmecp2.eu\/el\/hg204-huidagene\/?lang=en","og_locale":"el_GR","og_type":"article","og_title":"Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China) - DupMECP2","og_description":"A potential new perspective for the treatment of MECP2 duplication syndrome with Huidagene's CRIPSR-Cas13. The drug candidate HG204 demonstrated a significant reduction of MeCP2 protein and reversal of the symptoms.","og_url":"https:\/\/dupmecp2.eu\/el\/hg204-huidagene\/?lang=en","og_site_name":"DupMECP2","article_published_time":"2023-12-16T21:12:50+00:00","article_modified_time":"2023-12-20T18:44:05+00:00","og_image":[{"width":318,"height":112,"url":"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png","type":"image\/png"}],"author":"Caroline","twitter_card":"summary_large_image","twitter_misc":{"\u03a3\u03c5\u03bd\u03c4\u03ac\u03c7\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc":"Caroline","\u0395\u03ba\u03c4\u03b9\u03bc\u03ce\u03bc\u03b5\u03bd\u03bf\u03c2 \u03c7\u03c1\u03cc\u03bd\u03bf\u03c2 \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7\u03c2":"2 \u03bb\u03b5\u03c0\u03c4\u03ac"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#article","isPartOf":{"@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en"},"author":{"name":"Caroline","@id":"https:\/\/dupmecp2.eu\/#\/schema\/person\/b41e8cbba153cd974ee340386af279ee"},"headline":"Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China)","datePublished":"2023-12-16T21:12:50+00:00","dateModified":"2023-12-20T18:44:05+00:00","mainEntityOfPage":{"@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en"},"wordCount":313,"commentCount":0,"publisher":{"@id":"https:\/\/dupmecp2.eu\/#organization"},"image":{"@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage"},"thumbnailUrl":"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png","articleSection":["News"],"inLanguage":"el","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#respond"]}]},{"@type":"WebPage","@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en","url":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en","name":"Huidagene: \u039c\u03b9\u03b1 \u03c0\u03bf\u03bb\u03bb\u03ac \u03c5\u03c0\u03bf\u03c3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 CRISPR-CAS13 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03a3\u03b1\u03b3\u03ba\u03ac\u03b7 (\u039a\u03af\u03bd\u03b1) - DupMECP2","isPartOf":{"@id":"https:\/\/dupmecp2.eu\/#website"},"primaryImageOfPage":{"@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage"},"image":{"@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage"},"thumbnailUrl":"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png","datePublished":"2023-12-16T21:12:50+00:00","dateModified":"2023-12-20T18:44:05+00:00","description":"\u039c\u03b9\u03b1 \u03c0\u03b9\u03b8\u03b1\u03bd\u03ae \u03bd\u03ad\u03b1 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c1\u03cc\u03bc\u03bf\u03c5 \u03b4\u03b9\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd \u03c4\u03bf\u03c5 MECP2 \u03bc\u03b5 \u03c4\u03bf CRIPSR-Cas13 \u03c4\u03b7\u03c2 Huidagene. \u03a4\u03bf \u03c5\u03c0\u03bf\u03c8\u03ae\u03c6\u03b9\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf HG204 \u03ba\u03b1\u03c4\u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 MeCP2 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae \u03c4\u03c9\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd.","breadcrumb":{"@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#breadcrumb"},"inLanguage":"el","potentialAction":[{"@type":"ReadAction","target":["https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en"]}]},{"@type":"ImageObject","inLanguage":"el","@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#primaryimage","url":"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png","contentUrl":"https:\/\/dupmecp2.eu\/wp-content\/uploads\/2023\/12\/Huidagene-Logo.png","width":318,"height":112},{"@type":"BreadcrumbList","@id":"https:\/\/dupmecp2.eu\/hg204-huidagene\/?lang=en#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/dupmecp2.eu\/"},{"@type":"ListItem","position":2,"name":"News","item":"https:\/\/dupmecp2.eu\/category\/news\/?lang=en"},{"@type":"ListItem","position":3,"name":"Huidagene: A promising CRISPR-CAS13 technology from Shanghai (China)"}]},{"@type":"WebSite","@id":"https:\/\/dupmecp2.eu\/#website","url":"https:\/\/dupmecp2.eu\/","name":"DupMECP2","description":"\u0395\u0395","publisher":{"@id":"https:\/\/dupmecp2.eu\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/dupmecp2.eu\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"el"},{"@type":"Organization","@id":"https:\/\/dupmecp2.eu\/#organization","name":"DupMECP2","url":"https:\/\/dupmecp2.eu\/","logo":{"@type":"ImageObject","inLanguage":"el","@id":"https:\/\/dupmecp2.eu\/#\/schema\/logo\/image\/","url":"","contentUrl":"","caption":"DupMECP2"},"image":{"@id":"https:\/\/dupmecp2.eu\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/dupmecp2.eu\/#\/schema\/person\/b41e8cbba153cd974ee340386af279ee","name":"\u039a\u03b1\u03c1\u03bf\u03bb\u03af\u03bd\u03b1","sameAs":["https:\/\/dupmecp2.eu"],"url":"https:\/\/dupmecp2.eu\/el\/author\/417a2385dc37aa45\/"}]}},"_links":{"self":[{"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/posts\/22138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/comments?post=22138"}],"version-history":[{"count":0,"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/posts\/22138\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/media\/22150"}],"wp:attachment":[{"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/media?parent=22138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/categories?post=22138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dupmecp2.eu\/el\/wp-json\/wp\/v2\/tags?post=22138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}